Preface content

Science

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Diagnostics

The EURL FMD offers a full range of Foot-and-Mouth Disease diagnostics. This includes:

  • FMDV detection and serotyping by real time PCR, antigen ELISA and virus isolation.
  • Genotyping by sequencing (VP1 region) and phylogenetic analysis. This analysis can also be done on sequences supplied by other laboratories.
  • Vaccine matching studies by virus neutralisation tests (VNT) against a set number of vaccines.
  • Serological studies (including post vaccination studies) looking for structural (liquid phase blocking ELISA, solid phase competition ELISA and VNT).
  • PD50 and PPG in vivo cattle studies on FMDV vaccines.

Summaries of samples tested at The Pirbright Insitute

Summaries of testing in quarterly reports to the OIE

Please contact the laboratory if you want to send us samples to test

Training

Each year the EURL FMD runs a training course at The Pirbright Institute to train laboratory staff in various aspects of Foot-and-Mouth Disease diagnosis.

Other custom training and consultancy may also be available. Please contact the laboratory to discuss your requirements.

Proficiency Testing Scheme (PTS)

Each year the EURL FMD sends out a PTS to all the EU Member State National Laboratories (NRLs) to test the capability of the laboratories to diagnose Foot-and-Mouth Disease. Countries outside of the EU also participate through alternative funding or through self funding.

The panels are for both virological and serological FMDV detection and are available as infectious or non-infectious. Swine vesicular disease (SVD) is also added as a differential and laboratories are asked to identify those samples that contain SVD. Participants are asked to provide results for individual tests on each sample and, where multiple tests are used, to also provide an overall interpretation of the results for each sample. Where several samples have been supplied from a single case, the overall interpretation for the case should also be given.

A summary and overview of the results for each NRL is returned to each participant and an overall report is distributed to the NRLs and EU. The laboratories stay anonymous.

Please contact the laboratory if you are interested in participating

Research

Our research collaborations include a long-term association with the University of Glasgow and participation in European Networks of Excellence such as Epizone. We receive funding for our work from Defra, BBSRC and the EU, as well as a number of smaller contract research projects. We currently partner with other European laboratories on a range of applied and fundamental research projects including Epi-seq and Rapidia-Field, as well as initiatives to develop research and diagnostic capacity in Africa via the Southern African Centre for Infectious Disease Surveillance (SACIDS) and OIE.

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